Atmospheric and Oceanic Sciences
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Abstract The Configurable Reflectarray for Electronic Wideband Scanning Radiometry (CREWSR) is a future microwave imaging and sounding sensor that offers low-power, low-mass, low-cost, high-performance, and compatibility with Evolved Expendable Launch Vehicle (EELV) Secondary Payload Adapter (ESPA)-class small satellite systems. CREWSR will demonstrate a highly configurable SmallSat based microwave temperature sounder on several key capabilities: the spatial resolution, the sampling distance between two nearby field of views (FOVs), the ability to scan anywhere within its scene to allow angular sampling, the number of spectral channels, and the observation noise. These capabilities will optimize the observing strategy so that more observations can be made in regions that are data sensitive. This work focuses on evaluating three configurable aspects of CREWSR: the spatial resolution, the ground sample distance, and the angular samplings. A quick regional hybrid Observing System Simulation Experiment (OSSE) work was conducted to understand the added-value of CREWSR on Hurricane Ian (2022) forecast. Results show that assimilating both CREWSR and ATMS radiances in the early morning orbit improves the Hurricane Ian (2022) forecast on track and intensity. The finer spatial resolution can further improve the forecast. Most importantly, CREWSR radiances with the optimized observing strategy improves the forecast the best. These results demonstrate that a microwave sounder like CREWSR, with the capability to provide more observations in data sensitive region and fewer observations in data insensitive region, has the potential to further improve hurricane forecast beyond the current sensors’ capability.
Although high-frequency electromagnetic methods, such as Radio Magnetotellurics (RMT) and Controlled-Source Radio Magnetotellurics (CSRMT), are highly effective for shallow-to-medium depth exploration, deploying traditional transmitter–receiver setups remains labor-intensive and significantly slows down large-scale surveys. To overcome these logistical bottlenecks, we developed a mobile Ultra-Audio Frequency Electromagnetic (UAEM) measurement system. While the hardware is designed with dual-mode capabilities supporting conventional controlled-source operations, this paper specifically focuses on its application in a Signals of Opportunity (SOOP) mode. By utilizing pre-existing, stable anthropogenic signals, including Amplitude Modulation (AM) broadcasts and naval very low frequency communications, the system effectively functions as a broadband RMT receiver. Technical evaluations demonstrate that the instrument operates across a 1 Hz to 1000 kHz bandwidth with a high sampling rate of 2.5 MHz. Furthermore, it achieves a dynamic range of 143 dB and maintains an apparent resistivity measurement accuracy of better than 3%. Thanks to its modular, vehicle-towed design, the UAEM system enables continuous, on-the-move data acquisition wherever ambient field sources are available. This approach eliminates the need for dedicated transmitter deployment, fundamentally reducing exploration costs and boosting overall survey efficiency.
The detection of surface defects on smartphone components is a critical step in quality assurance for industrial manufacturing. However, existing deep learning-based methods struggle with the extreme variations in defect morphology and scale, while labeled training data remains scarce due to the high cost of expert annotation. To address these challenges, we propose a twofold solution. First, we introduce MSAdaNet, a Multi-Scale Adaptive Defect Detection Network, which integrates three novel modules: a Parallel Multi-Scale Feature Aggregation (PMSFA) backbone, a Focusing Diffusion Pyramid Network (FDPN) neck, and a Scale-Adaptive Shared Detection (SASD) head. Second, to combat data scarcity, we propose a novel data generation pipeline, creating the synthetic Smartphone Camera Bezel Dataset (SCBD) of 4936 images. Extensive experiments on both real-world and synthetic datasets validate our approach. On the challenging public SSGD, MSAdaNet achieves a state-of-the-art mAP@0.5 of 54.8%, outperforming prominent frameworks and improving upon the strong YOLOv11m baseline by +10.6 points in mAP@0.5 and +18.3 points in recall. Furthermore, on our synthetic SCBD, the model achieves an impressive 94.0% mAP@0.5, confirming the quality of our data generation pipeline and the robustness of our architecture across different data distributions. Ablation studies systematically confirm the significant contribution of each proposed module, validating MSAdaNet as an effective and efficient solution for industrial defect detection.
Alzheimer’s Disease (AD) is the leading cause of dementia worldwide, and early diagnosis is crucial to minimize neurological damage and loss of quality of life. Here, we report an electrochemical biosensor for detecting miRNAs 29a and 34a, potential non-invasive biomarkers associated with AD. The biosensor consisted of a glassy carbon electrode (GCE) modified with a novel nanohybrid of gold nanoparticles stabilized by 3-n-propyl(4-dimethylaminopyridinium) silsesquioxane chloride (AuNPs–Si4DMAP+Cl−). Thiolated anti-miRNA probes were immobilized separately on the GCE/AuNPs-Si4DMAP+Cl−, followed by BSA blocking. Target miRNAs were detected via hybridization with complementary probes using electrochemical impedance spectroscopy. The nanohybrid, characterized by spectroscopic and morphological techniques, significantly enhanced the electrochemical response and was effective detecting both miRNAs, showing suspension stability over 600 days. LOD and LOQ were 1.79 pM and 5.87 pM for miRNA-29a, and 2.21 pM and 11.01 pM for miRNA-34a. These results highlight the platform’s potential for electrochemical detection of these miRNAs in blood, supporting earlier detection of AD and other neurodegenerative diseases.
Fine-grained spatio-temporal action detection in continuous, unconstrained field videos remains a formidable challenge due to severe background clutter, high inter-class similarity, and the scarcity of domain-specific benchmarks. To address these limitations, we first introduce a large-scale Wintering-Crane Benchmark, providing dense, individual-level bounding box annotations for six complex behaviors across diverse habitat scenes. Leveraging this data, we propose AviaTAD-LGH, a real-time multi-task framework that incorporates auxiliary motion supervision into a dual-pathway 3D backbone to enhance feature discriminability. A critical bottleneck in such multi-task settings is the negative transfer caused by conflicting optimization objectives. To resolve this, we present Lightweight Gradient Harmonization (LGH), a plug-and-play optimization strategy that dynamically modulates task weights based on the cosine similarity of gradient directions. This mechanism effectively aligns optimization trajectories without introducing inference latency. Extensive experiments demonstrate that AviaTAD-LGH achieves a state-of-the-art mAP of 68.60%, surpassing strong public baselines by 7.44% and improving upon the single-task baseline by 2.80%, with significant gains observed on ambiguous dynamic classes. The proposed pipeline enables efficient, scalable ecological monitoring suitable for edge deployment.
The increasing demand for autonomous wireless sensors in Internet of Things (IoT) applications has intensified research on vibration energy harvesting, particularly in the low-frequency range where ambient vibrations are most prevalent. However, most vibration energy harvesters operate efficiently only at a single resonance mode, resulting in a narrow operational bandwidth and pronounced performance degradation under frequency detuning. To address this limitation, this paper proposes a multimodal hybrid piezoelectric–electromagnetic vibration energy harvester that exploits both the first and second resonance modes of a cantilever-based structure to achieve broadband low-frequency operation. The design is guided by the complementary utilization of strain-dominated and velocity-dominated regions associated with different vibration modes. Numerical modeling and finite element simulations are employed to investigate the influence of mass distribution, deformation characteristics, and relative velocity on energy conversion performance. A secondary cantilever carrying the electromagnetic coil is introduced to enhance the relative motion between the coil and the magnetic field, thereby extending the effective operational bandwidth. The experimental results demonstrate increased harvested power, improved energy conversion efficiency, and a significantly broadened effective frequency range compared to conventional single-mode piezoelectric and electromagnetic energy harvesters.
4D millimeter-wave radar provides high-precision ranging capability and exhibits strong robustness under adverse weather and low-visibility conditions, but its point clouds are relatively sparse and suffer from severe elevation-angle measurement noise. Monocular cameras, by contrast, provide rich semantic information and high recall, yet are fundamentally limited by scale ambiguity. To exploit the complementary characteristics of these two sensors, this paper proposes a radar-camera fusion 3D multi-object tracking framework that does not rely on complex 3D annotated data. First, on the radar signal-processing side, a Gaussian distribution-based adaptive angle compression method and IMU-based velocity compensation are introduced to effectively suppress measurement noise, and an improved DBSCAN clustering scheme with recursive cluster splitting and historical static-box guidance is employed to generate high-quality radar detections. Second, a disparity-domain metric depth recovery method is proposed. This method uses filtered radar points as sparse metric anchors, performs robust fitting with RANSAC, and applies Kalman filtering for temporal smoothing, thereby converting the relative depth output of the visual foundation model Depth Anything V2 into metric depth. Finally, a hierarchical fusion strategy is designed at both the detection and tracking levels to achieve stable cross-modal state association. Experimental results on a self-collected dataset show that the proposed method achieves an overall MOTA of 77.93%, outperforming single-modality baselines and other comparison methods by 11 to 31 percentage points. This study provides an effective solution for low-cost and robust environment perception in complex dynamic scenarios.
Collaboration between humans and robots (HRC) is advancing rapidly due to the intersection of robotics and generative artificial intelligence (GenAI). The current paper includes a systematic review of 103 studies on the role of generative models, including Generative Adversarial Networks (GANs), Variational Autoencoders (VAEs), diffusion models, and Large Language Models (LLMs) in improving the safety, trust, and adaptability of collaborative robotics using a PRISMA-based systematic approach. The review recognizes four major themed areas of GenAI-based safety frameworks—namely, data-driven simulation to synthesize hazards, predictive reasoning to forecast human motion, adaptive control to reduce risks dynamically, and trust-aware cognition to explain human–robot interaction. Findings indicate that generative models transform robotic safety from a reactive mechanism to proactive, contextual and interpretable systems. Nevertheless, real-time performance, interpretability, standard benchmarking, and ethical assurance are still some of the challenges to be overcome. The paper proposes a taxonomy linking generative modeling layers and physical, cognitive and ethical aspects of HRC safety, and gives a roadmap of certifiable hybrid systems with generative foresight and deterministic control. This synthesis provides a foundation for developing transparent, adaptive, and trustworthy collaborative robotic systems.
The rapid evolution of technologies for remotely monitoring people’s health has driven the creation of a variety of innovative solutions with potential to automate, transform, and optimize traditional healthcare delivery [...]
Ultrasound (US) imaging is a widely used diagnostic method in clinics. Real-time-generated US images are used for rapid diagnosis without harm to patients. The quality of US imaging highly depends on the skill of the physician due to the differences among physicians. Techniques for autonomous robotic ultrasound (AU-RUS) acquisitions are expected to become an effective means to improve the level of US diagnosis, reduce the workload of physicians, and improve the standardization of US imaging quality. This paper aims to summarize the current research status of techniques for AU-RUS acquisitions, and to discuss the research trends and challenges regarding related technologies. Firstly, the techniques for AU-RUS acquisitions and systems are outlined. The techniques for teleoperated or autonomous US acquisitions are briefly discussed. Representative RUS acquisition systems are introduced. Then, the current research status of AU-RUS acquisitions is reviewed from four research directions: force sensitivity and control, scanning path-planning and positioning, US treatment guidance, and US image processing technology and quality assessment optimization. This review provides a decision-oriented autonomy perspective by mapping typical methods to workflow components across the stages of perception, decision-making, and execution. We identify major deployment bottlenecks, including safety-verifiable autonomy and failure recovery, motion compensation under deformation, and the lack of standardized, clinically meaningful US image quality metrics. Finally, the shortcomings of current research are summarized and analyzed, and the research trends and challenges for AU-RUS acquisitions are prospected.
In challenging environments, there often exist problems of false alarms and missed detections in real-time kinematic (RTK) ambiguity resolution, which significantly reduce the reliability and availability of position information. To address these issues, a machine-learning method is proposed to conduct a correctness check on RTK ambiguity fixing, aiming to reduce the occurrences of false alarms and missed detections. The inter-system differential RTK model is adopted. Compared with the traditional RTK model, this model can provide an effective feature, namely the differential inter-system biases (DISB), to improve the accuracy of machine-learning classification. This is because when the RTK ambiguity is correctly fixed, the DISB usually appears as a stable constant. In addition to DISB, features that are strongly related to ambiguity fixing, such as the ratio value, DOP value, and residuals, are also comprehensively utilized. This method is verified by an open-source, large-scale, and diverse GNSS/SINS dataset—SmartPNT-POS. The experimental results show that, compared with the traditional method of relying solely on the empirical ratio value for ambiguity fixing verification, the missed detection probability of this method is reduced by 2%, the false-alarm probability is decreased by 29%, and the positioning accuracy is improved by approximately 7%. Moreover, compared with other features, the DISB feature provides the highest contribution rate in the machine-learning classification model.
(1) Background: Idiopathic scoliosis is a three-dimensional deformity, yet clinical and research decision-making still relies largely on radiographic Cobb angle measurements. As a radiation-free alternative, clinical assessment of transverse and sagittal plane deformities has gained importance. This study evaluated the concurrent validity and intra- and interrater reproducibility of continuous measurements of rib hump, thoracic kyphosis, and lumbar lordosis obtained using a smartphone application in adolescents with spinal deformities. (2) Methods: Adolescents aged 10–17 years with scoliosis (>10° Cobb) or hyperkyphosis (>50° Cobb) were recruited. Continuous measurements of angle of trunk rotation (ATR) during the Adams forward bend test and in standing position, as well as sagittal profile, were collected using the ISICO app mounted on a standardized plastic tool. Concurrent validity was assessed against a scoliometer using Spearman correlation, root mean square error, and Bland–Altman analysis, while reproducibility was evaluated using intraclass correlation coefficients, standard error of measurement, and minimal detectable change. (3) Results: Thirty-two adolescents were included for validation and intrarater analyses and 34 for interrater analyses. ATR measured during the Adams test showed very high correlation with the scoliometer and minimal bias, while standing ATR showed moderate correlation. Reliability was excellent for rib hump during forward bending and moderate for sagittal parameters, with the lowest values observed for lumbar lordosis. (4) Conclusions: These findings support the clinical use of continuous app-based ATR assessment and suggest that sagittal measurements may be useful with appropriate examiner training.
Spatiotemporal fusion aims to generate remote sensing images with both high spatial and high temporal resolution by integrating multi-source observations. However, significant spectral inconsistencies often arise when fusing images acquired at different spatial scales, which severely degrade the radiometric fidelity and temporal reliability of the fused results. Most existing methods focus on enhancing spatial details or temporal consistency, while the cross-scale spectral discrepancy between coarse- and fine-resolution images has not been sufficiently addressed. To tackle this issue, we propose a cross-scale spectral calibration framework for spatiotemporal fusion (XSC-Net), which explicitly models and corrects spectral responses across different spatial scales. The proposed method introduces a spatial feature refinement block to enhance spatially discriminative structures and a hierarchical spectral refinement block to adaptively calibrate channel-wise spectral representations. By jointly exploiting spatial and spectral correlations, the proposed framework effectively suppresses spectral distortion while preserving fine spatial details. Extensive experiments on the public CIA and LGC datasets indicate that XSC-Net compares favorably with state-of-the-art methods, demonstrating superior performance over established baselines. Furthermore, ablation studies verify the efficacy and contribution of the proposed architectural components.
This study investigates the wind field characteristics of long-span suspension bridges in mountain valleys terrain, with a particular focus on the disturbance effects caused by bridge structure on wind measurements. Field data are collected using the Wind3D 6000 LiDAR installed near the bridge. By comparing wind field characteristics before and after bridge completion, this study evaluates the influence of the bridge structure on both mean and turbulent wind characteristics. The findings show that the presence of the bridge tower and deck reduces the measured mean wind speed and modifies its probability distribution. The bridge tower increases the effective ground roughness coefficient, thereby attenuating the vertical wind speed gradient. In addition, the bridge tower raises the measured turbulence intensity, alters its probability distribution, and decreases the agreement between the turbulent wind power spectrum and the von Kármán spectrum. It is necessary to correct the data affected by these disturbances to improve the accuracy of wind load assessments for long-span bridges, thus enhancing the reliability of bridge structural operation.
Distinguishing Active from Inactive Tuberculosis (TB) on Chest X-rays presents a clinical challenge due to overlapping radiological signs. This study introduces Vision Mamba CGSM, a deep learning framework integrating a State Space Model (SSM) backbone with a Context-Guided Slot Mixing (CGSM) module. The SSM captures global anatomical context, while the CGSM module isolates subtle pathological features by applying localized spatial attention. We validated the model using a hierarchical diagnostic scheme covering Normal, Pneumonia, Active TB, and Inactive TB. Experimental evaluations demonstrate an accuracy of 92.96% and a Youden Index of 79.55% on the independent test set. In the specific binary classification of Active vs. Inactive TB, the model recorded a specificity of 97.04%, outperforming standard baseline architectures including ResNet152 and ViT-B. Additional validations on external datasets confirm the consistent generalization of the proposed feature extraction mechanism.
To address the challenge of detecting internal defects in medium-thick titanium alloy laser welds, a combined simulation and experimental study on ultrasonic testing was conducted. A finite element model employing a 5 MHz shear wave angle transducer for inspecting titanium alloy welds was established. An ultrasonic testing system was developed, incorporating a DPR300 pulser-receiver (JSR Ultrasonics, Pittsford, NY, USA) and an MSO5204 oscilloscope (RIGOL, Suzhou, China), and was calibrated using standard reference blocks. The inspection results for four prefabricated internal defects at various depths demonstrated that all defects were effectively detected, with the minimum detectable equivalent defect size reaching 1 mm. The measured signal-to-noise ratio (SNR) averaged 17.6 dB, validating the high sensitivity of the proposed system. The mean absolute error for defect localization was 0.438 mm, achieving a positioning accuracy better than 0.5 mm. This study indicates that the pro-posed method enables effective detection and accurate localization of internal defects in titanium alloy laser welds, providing critical technical support for laser welding quality assessment.
Flexible conductive hydrogels hold great promise in wearable electronics and biomonitoring applications, yet their practical use is constrained by issues such as poor low-temperature tolerance, susceptibility to dehydration, and limited multifunctional sensing capabilities. This study successfully synthesized a dual-conductive lithium-ion and calcium-ion hydrogel based on acrylamide/gelatin via a simplified low-temperature one-pot polymerization method. At 60 °C, mixing acrylamide, gelatin, lithium chloride, and calcium chloride within 40 min constructed a network structure featuring covalent bonds, ionic bonds, and hydrogen bonds. The resulting material exhibited exceptional extensibility with a break elongation of 1408.5% and tensile strength of 134.2 kPa while maintaining strong adhesion to nine different substrates. It retained flexibility at −20 °C and demonstrated minimal mass loss (3% of initial value) after 10 days of aging. As a sensor, this hydrogel reliably responds to pressure, temperature, large-amplitude body movements, and subtle physiological signals like pulse and vocal cord vibrations. In animal simulation monitoring, its electrical resistance signals increased linearly with model body weight and remained stable between −20 °C and 20 °C. These results demonstrate the hydrogel’s broad application potential in wearable sensing, ecological monitoring, and smart agriculture.
Artificial light at night (ALAN) data is widely used in urban function analysis and socio-economic activity monitoring, but its application at the micro-scale of cities still faces challenges. This study utilizes high spatial resolution SDGSAT-1 nighttime light data to explore the spatial heterogeneity of ALAN at the street scale in two representative Chinese cities—Beijing and Guangzhou. By integrating multi-source data (such as building vector data, road networks, and point of interest data), a multi-dimensional indicator system covering urban morphology, functional structure, and transportation accessibility is constructed. Based on this, the study employs a Geographically Weighted Random Forest (GWRF) model combined with the Shapley Additive Explanations (SHAP) method to deeply analyze the non-linear relationships between ALAN intensity and multiple driving factors, as well as their spatial variability. Results demonstrate the superiority of the GWRF model over global models in capturing spatial non-stationarity, with R2 values of 0.67 for Beijing and 0.74 for Guangzhou, compared to 0.62 and 0.71 for the random forest models, respectively. Road density is the dominant factor influencing nighttime light intensity in both Beijing and Guangzhou. However, the relationship between ALAN and its driving factors varies across these cities. In Beijing, a balanced multi-factor model is observed, whereas in Guangzhou, ALAN intensity is primarily driven by road density, with secondary influences from other factors like sky view factor. This study validates SDGSAT-1 for micro-scale analysis, offering a scientific basis for differentiated urban lighting planning.
Optical coherence tomography (OCT) is a non-invasive, high-resolution imaging technique widely used in medical diagnosis, biomedical research and other fields. It plays an important role in the early detection and accurate diagnosis of diseases. The superluminescent light-emitting diode (SLED) is the ideal light source for OCT systems, where the stability of its drive current and operating temperature directly determines the imaging quality of OCT. Existing driving and temperature control schemes for similar light sources predominantly rely on microcontrollers or field programmable gate arrays (FPGAs), a reliance which often results in complex system architectures and difficulties in balancing simplicity with control precision. To address these issues, a stable and compact SLED source driver module designed for OCT was developed in this study, integrating both a constant-current drive circuit and a temperature control circuit. The negative feedback control and improved current-limiting protection are employed in the constant-current drive circuit to maintain stable SLED operation and reduce the circuit footprint. A miniature dedicated temperature control chip is adopted in the temperature control circuit. The operating temperature of the SLED is acquired by linearizing the negative temperature coefficient (NTC) thermistor value and regulated through a proportional-integral-derivative (PID) compensation circuit. The size of the fabricated module (including casing) is less than 10 × 8 × 3 cm3. Experimental results show that the driver module achieves a drive current control accuracy of 0.1% and a temperature control accuracy of 0.01 °C. The output optical power fluctuation is less than 0.005 mW and the average axial resolution for OCT is 6.5992 μm with a standard deviation of 0.0107 μm. This light source driver module successfully balances control precision with structural simplicity, demonstrating excellent applicability in OCT systems.
Postural control relies on the integration of visual, vestibular, and somatosensory inputs under biomechanical constraints. Conventional Romberg testing provides limited quantitative insight, particularly regarding directional control and sensory dependence. Wearable inertial measurement units (IMUs) enable portable, multidimensional assessment of postural sway. Thirty healthy adults (15 females, 15 males) completed a modified Romberg protocol with systematic manipulation of stance (normal, tandem), visual condition (eyes open, eyes closed), and arm position (arms at sides, arms forward), including both left and right leading foot during tandem stance. Whole-body kinematics were recorded using a full-body IMU system comprising 17 wireless sensors. Center-of-mass (CoM) trajectories were derived from a 23-segment biomechanical model, and linear, spatial, and nonlinear sway metrics were computed. Statistical analyses were conducted using repeated-measures ANOVA, with significance set at p < 0.05. Visual deprivation significantly increased sway path length, mean sway velocity, and sway area across all stance conditions (p < 0.001). Tandem stance elicited greater mediolateral sway than normal stance (p < 0.001). Romberg ratios exceeded unity for all metrics and were significantly higher in tandem stance (p < 0.01). Arm position effects were negligible in normal stance but showed significant Vision × Arm interactions during tandem stance (p < 0.05). Leading foot position had no significant main effects. Combining a modified Romberg protocol with full-body IMU-based CoM analysis enables sensitive characterization of sensory dependence and directional postural control. Tandem stance with visual deprivation increases mediolateral postural demands under reduced base-of-support conditions, providing a more challenging context for evaluating directional postural control.
Understanding material surfaces from sparse visual cues is critical for applications in robotics, simulation and material perception. However, most existing methods rely on dense or full scene observations, limiting their effectiveness in constrained or partial view environments. This gap highlights the need for models capable of inferring surfaces’ properties from extremely limited visual information. To address this challenge, we introduce SMARC, a unified model for Surface MAterial Reconstruction and Classification from minimal visual input. By giving only a single 10% contiguous patch of the image, SMARC recognizes and reconstructs the full RGB surface while simultaneously classifying the material category. Our architecture combines a Partial Convolutional U-Net with a classification head, enabling both spatial inpainting and semantic understanding under extreme observation sparsity. We compared SMARC against five models including convolutional autoencoders, Vision Transformer (ViT), Masked Autoencoder (MAE), Swin Transformer and DETR using the Touch and Go dataset of real-world surface textures. SMARC achieves the highest performance among the evaluated methods with a PSNR of 17.55 dB and a surface classification accuracy of 85.10%. These results validate the effectiveness of SMARC in relation to surface material understanding and highlight its potential for deployment in robotic perception tasks where visual access is inherently limited.
Ultrasound enables radiation-free longitudinal monitoring of scoliosis, but rib shadowing and speckle noise often obscure vertebral structures. Current deep-learning methods present results in terms of localisation accuracy, without directly measuring anatomical completeness. We introduce a vertebra-level completeness model that includes a YOLO-based detection framework and an explicit representation of completeness, the Vertebra Presence Matrix (VPM). The VPM provides visibility into detections across 17 ordinal vertebral levels (T1–T12, L1–L5), allowing us to measure completeness across anatomy rather than just detections. Thoracolumbar ultrasound scans were annotated and divided into train/test sets using a patient-wise split to avoid data leakage. Four model variants were evaluated, including full-spine and vertebra-centric crop representations with single-class and 17-class detection heads. The full-spine detector was less stable in regions of high anatomical variability, such as the upper thoracic and lower lumbar spine. Crops of individual vertebrae were more stable under partial fields of view. The 17-class crop model achieved an mAP50 of 0.929 and a scan-level completeness score of 0.74 using the VPM. These results demonstrate that vertebral completeness can be explicitly quantified and integrated with localisation-based metrics for completeness-aware automated scoliosis evaluation.
Hypochlorous acid (HClO) is widely used as a low-cost and effective disinfectant; however, its instability under heat and light necessitates simple and reliable monitoring methods. Herein, we report a morphology-evolving thin-film colorimetric sensor that enables intuitive visual detection of HClO through simultaneous color and pattern transitions. The sensor integrates two polymer films with distinct charge-state response behaviors, patterned in X-shaped and circular geometries on a single substrate. Upon exposure to HClO, chlorine-induced modification of amide and amine groups alters the surface charge states, thereby switching the adsorption preference for anionic and cationic dyes. This mechanism results in a pronounced transformation from a blue X-shaped motif to a red circular pattern, enabling direct visual discrimination between different HClO concentrations. Quantitative analysis of RGB values confirmed semi-quantitative detection in the sub-millimolar to millimolar range. The sensor exhibited a linear response in the range of 0–3 mM (R2 > 0.979) with a limit of detection of 0.103 mM. The sensor further demonstrated practical applicability by tracking photodecomposition of a commercial disinfectant. This work demonstrates pattern-coupled colorimetric sensing as a straightforward, user-friendly approach for HClO monitoring.
Excessive accumulation of copper ions (Cu2+) in the environment and biological systems poses severe risks to ecological balance and human health, necessitating accurate detection and monitoring of Cu2+. Schiff base derivatives with favorable optical properties provide an efficient strategy for copper ion recognition. In this paper, fluorescent probe L (5-methyl-2-hydroxybenzaldehyde-(7-diethylaminocoumarin-3-formyl) hydrazone) was synthesized through a three-step reaction using 4-diethylaminosalicylaldehyde and diethyl malonate as starting materials. The structure of probe L was confirmed by melting point analysis, infrared spectroscopy, and nuclear magnetic resonance. Single-crystal X-ray analysis revealed that probe L crystallized into a triclinic lattice with space group P1−. Optical investigations, including UV–Vis spectroscopy, fluorescence spectroscopy, and aggregation-induced emission studies, demonstrated highly sensitive and selective fluorescence “turn-off” behavior of probe L towards Cu2+ ions in DMSO, with negligible interference from other metal ions. Job’s plot and crystallographic analysis revealed a 1:1 binding stoichiometry between probe L and Cu2+, forming the complex [Cu(L)]. Fluorescence titration experiments revealed a binding constant (Kb) of 5.2 × 106 L/mol and a detection limit of 7.8 × 10−7 mol/L, indicating excellent sensitivity. These results suggest that probe L has considerable promise for Cu2+ detection in aqueous environments, with potential applications in environmental monitoring and public health protection.
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